SCHEMBL2701285

SCHEMBL2701285

CCCCCCCCCCCC(=O)O[Si](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.57
LMNA P02545 2/20 0.53
PAM P19021 2/20 0.52
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 1/20 0.50
TSHR P16473 5/20 0.48
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
HDAC11 Q96DB2 5/20 0.48
GPR84 Q9NQS5 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30801438 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL9436470 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL30974650 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL155828 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL17578973 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL11093551 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL30974645 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL6554451 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL6554418 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL30849931 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117550995-A Synthesis method of fatty acyl amino acid surfactant 衢州科峰新材料有限公司 2024-02-13 CN disclosed
US-20170065514-A1 CROSS-LINKED COMPOSITION AND COSMETIC COMPOSITION COMPRISING THE SAME DOW SILICONES CORPORATION 2017-03-09 US disclosed
US-20150232721-A1 MOISTURE-CURING HOT-MELT ADHESIVE COMPOUND CONTAINING POLYALDIMINE SIKA TECHNOLOGY AG (CH) 2015-08-20 US disclosed
US-8932721-B2 Laminates joined by polyurethane hot-melt adhesive and process for bonding plasticizer-containing plastics SIKA TECHNOLOGY AG (CH) 2015-01-13 US disclosed
US-20120107616-A1 Laminates Joined by Polyurethane Hot-Melt Adhesive and Process for Bonding Plasticizer-Containing Plastics SIKA TECHNOLOGY AG (CH) 2012-05-03 US disclosed
US-20100291368-A1 MOISTURE-CURING HOT-MELT ADHESIVE COMPOUND CONTAINING POLYALDIMINE SIKA TECHNOLOGY AG (CH) 2010-11-18 US disclosed
EP-1990387-B1 Composite layer body joined with polyurethane holt melt glue and method for gluing plastics containing dilutents SIKA TECHNOLOGY AG (CH) 2010-07-21 EP disclosed
EP-1923445-B1 Polyaldimine containing moisture curable hotmelt adhesive composition SIKA TECHNOLOGY AG (CH) 2009-06-24 EP disclosed
US-20080280145-A1 moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive SIKA TECHNOLOGY AG (CH) 2008-11-13 US disclosed
EP-1990387-A1 Composite layer body joined with polyurethane holt melt glue and method for gluing plastics containing dilutents Sika Technology AG (CH) 2008-11-12 EP disclosed
EP-1923445-A1 Polyaldimine containing moisture curable hotmelt adhesive composition Sika Technology AG (CH) 2008-05-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170065514-A1 CROSS-LINKED COMPOSITION AND COSMETIC COMPOSITION COMPRISING THE SAME H1-0, H1-2, H1-3 DGKA 3623/4885LMNA 3633/4885PAM 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.