SCHEMBL2701352

SCHEMBL2701352

C#CC=CCc1cc[c]cc1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3515160 0.73 MAOB (0.39) MAOB
SCHEMBL93627 0.73 MAOB (0.39) MAOB
SCHEMBL6298669 0.73 MAOB (0.71) MAOB
SCHEMBL2116097 0.73 MAOB (0.39) MAOB
SCHEMBL9818852 0.71 MAOB (0.42) MAOB
SCHEMBL4630599 0.71 MAOB (0.42) MAOB
SCHEMBL6832149 0.71 MAOB (0.42) MAOB
SCHEMBL9559673 0.70 MAOB (0.41) MAOB
SCHEMBL7822556 0.69
SCHEMBL4934257 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287161-B1 Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders OTSUKA PHARMA CO LTD (JP) 2012-05-09 EP disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed