SCHEMBL4630599

SCHEMBL4630599

CCC=CCc1cc[c]cc1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.42
KCNH2 Q12809 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818852 1.00 MAOB (0.42) MAOBKCNH2
SCHEMBL7984426 0.83 MAOB (0.39) MAOBKCNH2
SCHEMBL27448664 0.79 TOP1 (0.39) MAOBKCNH2
SCHEMBL6298669 0.79 MAOB (0.71) MAOBKCNH2
SCHEMBL2116097 0.79 MAOB (0.39) MAOB
SCHEMBL93627 0.79 MAOB (0.39) MAOB
SCHEMBL25306764 0.78 KCNH2 (0.34) KCNH2
SCHEMBL9401079 0.78 TRPV1 (0.40) KCNH2
SCHEMBL9401077 0.78 TRPV1 (0.40) KCNH2
SCHEMBL6832149 0.77 MAOB (0.42) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137133-A2 PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES BASF SE (DE) 2023-07-20 WO disclosed
CN-107250091-A Method for synthesizing optically active carbonyl compound 巴斯夫欧洲公司 2017-10-13 CN disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
EP-1913007-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2008-04-23 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
WO-2007012655-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2007-02-01 WO disclosed
CN-1029227-C Composition for denatured denaturation or protection agent for nerve cell and process for preparing benzene derivatives used for composition OTSUKA PHARMA CO LTD (JP) 1995-07-05 CN disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
CN-1044807-A Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition OTSUKA PHARMA CO LTD (JP) 1990-08-22 CN disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed