SCHEMBL2701449

SCHEMBL2701449

Cc1ccc2cccc3c2c1C(=O)C3=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
CES1 P23141 2/20 0.59
CES2 O00748 1/20 0.59
BCHE P06276 1/20 0.59
MCL1 Q07820 1/20 0.59
CYP3A4 P08684 3/20 0.47
PABPC1 P11940 3/20 0.47
DNMT1 P26358 3/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 3/20 0.43
KDM4E B2RXH2 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CYP1B1 Q16678 1/20 0.43
MEN1 O00255 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13146013 0.81 NQO1 (0.43) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL27825788 0.81 ALDH1A1 (0.59) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL27833733 0.78 ALDH1A1 (0.61) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL30420926 0.78 ALDH1A1 (0.61) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL11312965 0.77 ALDH1A1 (0.59) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL29804648 0.77 ALDH1A1 (0.59) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL21450709 0.77 PARP1 (0.63) ALDH1A1CES1CES2BCHEMCL1
SCHEMBL827965 0.77 MAPT (0.55) ALDH1A1CES1CES2BCHEMCL1
Acenaphthoquinone SCHEMBL2156555 0.76 ALDH1A1 (1.00) ALDH1A1CES1CES2BCHEMCL1
Acenaphthoquinone SCHEMBL29586645 0.76 ALDH1A1 (1.00) ALDH1A1CES1CES2BCHEMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102466990-B Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2013-11-06 CN disclosed
US-8507162-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-08-13 US disclosed
EP-2447781-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2013-01-16 EP disclosed
CN-102466990-A Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK 2012-05-23 CN disclosed
US-20120107735-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-05-03 US disclosed
EP-2447781-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2012-05-02 EP disclosed