SCHEMBL2701507

SCHEMBL2701507

c1ccc(N(c2cccc3ccccc23)c2cc(N(c3ccccc3)c3cccc4ccccc34)c3ccc4c(N(c5ccccc5)c5cccc6ccccc56)cc(N(c5ccccc5)c5cccc6ccccc56)c5ccc2c3c54)cc1.c1ccc(N(c2cccc3ccccc23)c2cc(N(c3ccccc3)c3cccc4ccccc34)c3ccc4c(N(c5ccccc5)c5cccc6ccccc56)cc(N(c5ccccc5)c5cccc6ccccc56)c5ccc2c3c54)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.47
L3MBTL1 Q9Y468 1/20 0.36
HPRT1 P00492 2/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP1A2 P05177 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
CDC25B P30305 1/20 0.35
ATM Q13315 1/20 0.35
ERBB2 P04626 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35
ACHE P22303 1/20 0.35
AHR P35869 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1249647 1.00 SIGMAR1 (0.47) SIGMAR1L3MBTL1HPRT1ALDH1A1CYP3A4
SCHEMBL13321023 0.92 HPRT1 (0.45) SIGMAR1HPRT1ALDH1A1CYP1A2TSHR
SCHEMBL13320935 0.91 SIGMAR1 (0.46) SIGMAR1L3MBTL1ALDH1A1CYP3A4CYP1A2
SCHEMBL18198289 0.91 SIGMAR1 (0.44) SIGMAR1L3MBTL1ALDH1A1CYP3A4CYP1A2
SCHEMBL12576995 0.89 SIGMAR1 (0.40) SIGMAR1L3MBTL1ALDH1A1CYP1A2HPGD
SCHEMBL12577109 0.89 SIGMAR1 (0.40) SIGMAR1L3MBTL1ALDH1A1CYP3A4TSHR
SCHEMBL13900004 0.89 SIGMAR1 (0.47) SIGMAR1L3MBTL1HPRT1ALDH1A1CYP3A4
SCHEMBL13321032 0.89 SIGMAR1 (0.46) SIGMAR1L3MBTL1HPRT1ALDH1A1CYP3A4
SCHEMBL30799092 0.89 SIGMAR1 (0.51) SIGMAR1L3MBTL1HPRT1ALDH1A1CYP3A4
SCHEMBL292397 0.89 SIGMAR1 (0.51) SIGMAR1L3MBTL1HPRT1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403354-B1 1,3,6,8 tetrasubstituted pyrene compound, organic EL element using the same, and organic EL display using the same FUJIFILM CORP (JP) 2012-05-09 EP disclosed
EP-1403354-A1 1,3,6,8 tetrasubstituted pyrene compound, organic EL element using the same, and organic EL display using the same FUJITSU LIMITED (JP) 2004-03-31 EP disclosed