Acetoacetic Acid

Acetoacetic Acid

SCHEMBL2701583

CC(=O)CC(=O)O.CC(=O)CC(=O)O.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.48
KDM5C P41229 2/20 0.48
EGLN1 Q9GZT9 2/20 0.48
PHF8 Q9UPP1 2/20 0.48
KDM2A Q9Y2K7 2/20 0.48
KDM6B O15054 1/20 0.48
LDHA P00338 1/20 0.47
SRR Q9GZT4 1/20 0.47
LMNA P02545 1/20 0.43
SLC15A2 Q16348 1/20 0.43
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
HTT P42858 1/20 0.38
FFAR3 O14843 3/20 0.37
ALDH1A1 P00352 2/20 0.37
GLRA1 P23415 1/20 0.37
SLC6A9 P48067 1/20 0.37
OR51E2 Q9H255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL711498 1.00 KDM4E (0.48) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL29107389 0.90 EGLN1 (0.50) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL1144213 0.90 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL1406366 0.90 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL649090 0.90 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL10941648 0.90 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL31420005 0.90
Acetoacetic Acid SCHEMBL28972036 0.90 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL21402364 0.90
Acetoacetic Acid SCHEMBL6620 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805075-B Synthesis method of bis [3, 3-di (3-tert-butyl-4-hydroxyphenyl) butyric acid ] ethylene diester 江苏福基新材料研究院有限公司 2023-01-17 CN claimed
CN-115297842-A Deformable hydrogel particles and pharmaceutical composition for treating cancer comprising same 斯科拉福克斯特有限公司 2022-11-04 CN claimed
CN-114805075-A Synthesis method of bis [3, 3-di (3-tert-butyl-4-hydroxyphenyl) butyric acid ] ethylene ester 江苏福基新材料研究院有限公司 2022-07-29 CN claimed
US-20220056171-A1 Isocyanate Free Binder ARXADA AG (CH) 2022-02-24 US claimed
EP-3909702-A1 ISOCYANATE FREE BINDER Lonza Solutions AG (CH) 2021-11-17 EP claimed
EP-3860780-A1 ISOCYANATE FREE BINDER Lonza Solutions AG (CH) 2021-08-11 EP claimed
WO-2020127611-A1 ISOCYANATE FREE BINDER LONZA LTD (CH) 2020-06-25 WO claimed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US claimed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US claimed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US claimed
US-20070173602-A1 Encapsulated Michael addition catalyst ENERGY, UNITED STATES DEPARTMENT OF 2007-07-26 US claimed
EP-1769094-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS Reaxa Limited (GB) 2007-04-04 EP claimed
WO-2005123971-A2 SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS REAXA LIMITED (GB) 2005-12-29 WO claimed
US-6187385-B1 For waterborne coatings applied to corroded or rusty metal substrates EASTMAN CHEMICAL COMPANY 2001-02-13 US claimed
EP-0971989-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 2000-01-19 EP claimed
US-5922790-A ACETOACETATE ESTERS AS ADDED TO WATERBORNE COMPOSITIONS CONTAINING ALKYD RESINS; IMPROVED ADHESION, ESPECIALLY TO CORRODED METAL SUBSTRATES EASTMAN CHEMICAL COMPANY (US) 1999-07-13 US claimed
WO-1998030639-A1 NON-POLYMERIC ACETOACETATES AS ADHESION PROMOTING COALESCING AGENTS EASTMAN CHEMICAL COMPANY (US) 1998-07-16 WO claimed
WO-1995016749-A1 AQUEOUS TWO-PART ISOCYANATE-FREE CURABLE, POLYURETHANE RESIN SYSTEMS GUERTIN BROS. COATINGS AND SEALANTS LTD. (CA) 1995-06-22 WO claimed
US-5017649-A Low temperature crosslinking EASTMAN KODAK COMPANY (US) 1991-05-21 US claimed
US-4209467-A COBALT COMPLEX CATALYST DAICEL LTD. (JP) 1980-06-24 US claimed