SCHEMBL2701883

SCHEMBL2701883

CCCCC(CC)CP(=O)(O)CCCC.[Ni]

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GABBR2 O75899 1/20 0.46
GABRR1 P24046 1/20 0.46
GABBR1 Q9UBS5 1/20 0.46
ALDH1A1 P00352 3/20 0.45
FDPS P14324 5/20 0.44
CA2 P00918 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 2/20 0.39
ATM Q13315 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4706907 0.98 CYP3A4 (0.47) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL673379 0.96 CYP3A4 (0.46) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL212573 0.96 CYP3A4 (0.46) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL3960944 0.96 CYP3A4 (0.46) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL672724 0.96 CYP3A4 (0.46) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL30844479 0.91 LPAR3 (0.48) CYP3A4L3MBTL1ALDH1A1FDPSTRPM8
SCHEMBL10419775 0.91 CYP3A4 (0.47) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL641159 0.90 ALDH1A1 (0.50) CYP3A4L3MBTL1ALDH1A1FDPSCA2
SCHEMBL9622654 0.89 CYP3A4 (0.46) CYP3A4L3MBTL1GABBR2GABRR1GABBR1
SCHEMBL228798 0.88 ALDH1A1 (0.52) CYP3A4L3MBTL1ALDH1A1FDPSCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
WO-2023129959-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2023-07-06 WO disclosed
US-20230144912-A1 METAL-BASED CATALYST FOR PRODUCING POLYDIENES BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2023-05-11 US disclosed
WO-2012154721-A1 PROCESSES FOR THE PREPARATION OF HIGH-CIS POLYDIENES BRIDGESTONE CORPORATION (JP) 2012-11-15 WO disclosed
US-20120255661-A1 PROCESSES FOR PREPARATION OF CYCLIC AND ACYCLIC DIENE COPOLYMER AND RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2012-10-11 US disclosed
US-20120108755-A1 BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE BRIDGESTONE CORPORATION (JP) 2012-05-03 US disclosed
US-20100137520-A1 Branched Polymers and Methods for Their Synthesis and Use BRIDGESTONE CORPORATION (JP) 2010-06-03 US disclosed
US-7585805-B2 polymerization catalyst containing e.g.a combination or reaction product of triisobutylaluminum an alkylating agent, Ni(II) neodecanoate borate as nickel compound, trifluoride/n-hexanol complex as F2 compound and tin tetrachloride as Cl2 compound to polymerize 1,3-butadiene to cis-1,4-polybutadiene BRIDGESTONE CORPORATION 2009-09-08 US disclosed
US-20080255327-A1 addition polymerization of conjugated polyene monomer in the presence of polymerization catalysts comprising a mixture of a nickel-containing compound, an alkylating agent, a fluorine-containing compound, a carboxylic acid and an alcohol; controlling gelation, branching and molecular weight; efficiency BRIDGESTONE CORPORATION (JP) 2008-10-16 US disclosed
US-20070117942-A1 Nickel-based catalyst composition BRIDGESTONE CORPORATION 2007-05-24 US disclosed
EP-1788003-A1 Nickel-based catalyst composition Bridgestone Corporation (JP) 2007-05-23 EP disclosed
US-6699813-B2 COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS BRIDGESTONE CORPORATION (JP) 2004-03-02 US disclosed
US-20030176276-A1 Lanthanide-based catalyst composition for the manufacture of polydienes BRIDGESTONE CORPORATION (JP) 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB CYP3A4 1440/4885L3MBTL1 212/4885GABBR2 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.