SCHEMBL27022331

SCHEMBL27022331

CC(=O)Nc1ncc(CN2CCN(C(=O)OC(C)(C)C)CC2)s1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OGA O60502 18/20 0.60
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29057516 0.87 F13A1 (0.52) OGASMN1; SMN2
SCHEMBL27022332 0.83 OGA (0.57) OGA
SCHEMBL1002565 0.82 SMN1; SMN2 (0.50) OGASMN1; SMN2
SCHEMBL29057519 0.81 MAP4K4 (0.43) OGASMN1; SMN2
SCHEMBL20281964 0.81 SMN1; SMN2 (0.74) OGASMN1; SMN2
SCHEMBL13128868 0.81 SMN1; SMN2 (0.53) OGASMN1; SMN2
SCHEMBL16113448 0.80 SMN1; SMN2 (0.76) OGASMN1; SMN2
SCHEMBL1722296 0.79 SMN1; SMN2 (0.76) OGASMN1; SMN2
SCHEMBL27099904 0.78 OGA (0.65) OGASMN1; SMN2
SCHEMBL22433256 0.78 OGA (0.54) OGASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 US disclosed
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE OGA 1/4885SMN1; SMN2 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.