⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083169 | 0.82 | — | — | |
| SCHEMBL19112682 | 0.82 | — | — | |
| SCHEMBL6287791 | 0.79 | — | — | |
| SCHEMBL9521799 | 0.76 | — | — | |
| SCHEMBL4596443 | 0.71 | — | — | |
| SCHEMBL723753 | 0.70 | — | — | |
| SCHEMBL18291069 | 0.70 | — | — | |
| SCHEMBL6914301 | 0.67 | — | — | |
| SCHEMBL5555 | 0.65 | — | — | |
| SCHEMBL40927 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912400-A | The synthetic method of perfluorovinyl sulfide perfluor iodoethyl ether and its intermediate | 中国科学院上海有机化学研究所 | 2019-06-21 | — | — | CN | claimed |
| EP-4097155-B1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2025-08-20 | — | — | EP | disclosed |
| US-12037463-B2 | Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2024-07-16 | — | — | US | disclosed |
| US-12024597-B2 | Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2024-07-02 | — | — | US | disclosed |
| CN-117327093-A | Synthesis method of Biolimus A9 | 福建省微生物研究所 | 2024-01-02 | — | — | CN | disclosed |
| US-20230227613-A1 | ANTIMICROBIAL OPHTHALMIC DEVICES COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2023-07-20 | — | — | US | disclosed |
| US-20230212357-A1 | WOUND DRESSINGS COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | CLEARLAB SG PTE LTD (SG) | 2023-07-06 | — | — | US | disclosed |
| US-11649325-B2 | Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2023-05-16 | — | — | US | disclosed |
| EP-4097155-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab SG Pte Ltd (SG) | 2022-12-07 | — | — | EP | disclosed |
| US-20210246270-A1 | ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF | Clearlab Sg Pte Ltd. (SG) | 2021-08-12 | — | — | US | disclosed |
| US-20040152725-A1 | Methods of treating cancer | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | US | disclosed |
| EP-1408950-A2 | METHODS OF TREATING CYTOKINE MEDIATED DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20030130309-A1 | Methods of treating cytokine mediated diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-07-10 | — | — | US | disclosed |
| US-6525046-B1 | Inhibits inflammatory cytokines such as interleukin-1 and tumor necrosis factor; 1-(5-(2-hydroxy-1,1-dimethyl-ethyl) -2-p-tolyl-2H-pyrazol-3-yl)-3- (4-(2- morpholin-4-yl-ethoxy)-naphthalen-1-yl)-urea | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-02-25 | — | — | US | disclosed |
| WO-2003005999-A2 | METHODS OF TREATING CYTOKINE MEDIATED DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-01-23 | — | — | WO | disclosed |
| EP-0868438-A4 | SELECTIVE ALKYLATIONS OF CYCLODEXTRINS AT THE LEVELS OF MINIMAL EFFECTIVE BASICITY | PITHA JOSEF (US) | 2001-02-07 | — | — | EP | disclosed |
| US-6001821-A | FUSING 1,4 DIOXANE RIGHTS TO GLUCOPYRANOSYL RESIDUES | ROQUETTE FRERES (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5935941-A | Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity | ROQUETTE FRERES (FR) | 1999-08-10 | — | — | US | disclosed |
| EP-0868438-A1 | SELECTIVE ALKYLATIONS OF CYCLODEXTRINS AT THE LEVELS OF MINIMAL EFFECTIVE BASICITY | Pitha, Josef (US) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997022630-A1 | SELECTIVE ALKYLATIONS OF CYCLODEXTRINS AT THE LEVELS OF MINIMAL EFFECTIVE BASICITY | PITHA JOSEF (US) | 1997-06-26 | — | — | WO | disclosed |