⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083169 | 0.96 | — | — | |
| SCHEMBL270261 | 0.79 | — | — | |
| SCHEMBL9521799 | 0.74 | — | — | |
| SCHEMBL19112682 | 0.72 | — | — | |
| SCHEMBL7517602 | 0.72 | — | — | |
| SCHEMBL10340745 | 0.68 | TSHR (0.48) | — | |
| SCHEMBL4599851 | 0.67 | — | — | |
| SCHEMBL2047670 | 0.67 | — | — | |
| SCHEMBL4596443 | 0.62 | — | — | |
| SCHEMBL10580773 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11607460-B2 | Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway | SEAGEN INC. (US) | 2023-03-21 | — | — | US | disclosed |
| US-11213588-B2 | Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same | SERINA THERAPEUTICS, INC. (US) | 2022-01-04 | — | — | US | disclosed |
| US-20190184029-A1 | SYNERGISTIC EFFECTS BETWEEN AURISTATIN-BASED ANTIBODY DRUG CONJUGATES AND INHIBITORS OF THE PI3K-AKT MTOR PATHWAY | SEAGEN INC. | 2019-06-20 | — | — | US | disclosed |
| US-10299478-B2 | Pyrazolyltriazolylpyridines as pesticides | BAYER ANIMAL HEALTH GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20190134208-A1 | MULTIFUNCTIONAL FORMS OF POLYOXAZOLINE COPOLYMERS AND DRUG COMPOSITIONS COMPRISING THE SAME | SERINA THERAPEUTICS (AL), INC. | 2019-05-09 | — | — | US | disclosed |
| US-6867161-B1 | Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |