⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146532 | 0.86 | ALDH1A1 (0.54) | — | |
| SCHEMBL270348 | 0.85 | — | — | |
| SCHEMBL921220 | 0.83 | ALDH1A1 (0.63) | — | |
| SCHEMBL499996 | 0.81 | ALDH1A1 (0.67) | — | |
| SCHEMBL3392080 | 0.81 | ALDH1A1 (0.67) | — | |
| SCHEMBL3391471 | 0.81 | ALDH1A1 (0.67) | — | |
| SCHEMBL3389147 | 0.81 | ALDH1A1 (0.67) | — | |
| SCHEMBL3387052 | 0.81 | ALDH1A1 (0.67) | — | |
| SCHEMBL11060991 | 0.81 | ALDH1A1 (0.61) | — | |
| SCHEMBL7094868 | 0.81 | ALDH1A1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 679 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045251-B1 | COMPOUND THAT CAN INHIBIT UBC13-UEV INTERACTIONS, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC USES | CONSEJO SUPERIOR INVESTIGACION (ES) | 2015-11-18 | — | — | EP | claimed |
| US-8785430-B2 | Compound that can inhibit UBC13-UEV interactions, pharmaceutical compositions and therapeutic uses | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2014-07-22 | — | — | US | claimed |
| EP-1555266-B1 | REMEDIES OR PREVENTIVES FOR URINARY INCONTINENCE AND MORPHINAN DERIVATIVES HAVING NITROGEN-CONTAINING HETEROCYCLIC GROUP | TORAY INDUSTRIES (JP) | 2014-05-21 | — | — | EP | claimed |
| CN-103459382-A | Heterocyclic compounds for the inhibition of pask | BIOENERGENIX LLC | 2013-12-18 | — | — | CN | claimed |
| US-20130237529-A1 | COMPOUND THAT CAN INHIBIT UBC13-UEV INTERACTIONS, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC USES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS | 2013-09-12 | — | — | US | claimed |
| CN-102656163-A | Heterocyclic compounds for the inhibition of PASK | BIOENERGENIX | 2012-09-05 | — | — | CN | claimed |
| US-8252786-B2 | Compound that can inhibit UBC13-UEV interactions, pharmaceutical compositions and therapeutic uses | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2012-08-28 | — | — | US | claimed |
| US-20110160189-A1 | COMPOUND THAT CAN INHIBIT UBC13-UEV INTERACTIONS, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC USES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2011-06-30 | — | — | US | claimed |
| EP-2045251-A1 | COMPOUND THAT CAN INHIBIT UBC13-UEV INTERACTIONS, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC USES | Consejo Superior de Investigaciones Cientificas (ES) | 2009-04-08 | — | — | EP | claimed |
| US-7320984-B2 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group | TORAY INDUSTRIES, INC. (JP) | 2008-01-22 | — | — | US | claimed |
| EP-1121118-A1 | FORMAMIDES AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2001-08-08 | — | — | EP | claimed |
| EP-0718281-B1 | CYCLOHEXANEDIUREA DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NISSIN FOOD PRODUCTS LTD (JP) | 2001-06-27 | — | — | EP | claimed |
| US-6248719-B1 | Tricyclic 3-keto derivatives of 6-O-methylerthromycin | PFIZER INC | 2001-06-19 | — | — | US | claimed |
| US-6191150-B1 | METALLOPROTEASE INHIBITOR | GLAXO WELLCOME INC. | 2001-02-20 | — | — | US | claimed |
| US-6172064-B1 | METALLOPROTEASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | GLAXO WELLCOME INC. | 2001-01-09 | — | — | US | claimed |
| WO-2000012083-A1 | FORMAMIDES AS THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2000-03-09 | — | — | WO | claimed |
| WO-1999062920-A1 | TRICYCLIC 3-KETO DERIVATIVES OF 6-O-METHYLERYTHROMYCIN | PFIZER PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-0952157-A1 | 9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | claimed |
| US-3968109-A | ANTIBIOTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-06 | — | — | US | claimed |