Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21986792 | 0.98 | DPP4 (0.35) | DPP4DPP8KDM4EALDH1A1MAPT | |
| SCHEMBL21986777 | 0.83 | MTNR1A (0.34) | KDM4EALDH1A1MAPTNSD2USP7 | |
| SCHEMBL27228498 | 0.77 | MAPT (0.42) | KDM4EALDH1A1MAPTNSD2USP7 | |
| SCHEMBL19538835 | 0.76 | PDE3B (0.40) | KDM4EALDH1A1MAPTNSD2MTNR1A | |
| SCHEMBL21986797 | 0.75 | — | — | |
| SCHEMBL23508730 | 0.73 | PTPN11 (0.37) | KDM4EALDH1A1MAPTNSD2PTPN11 | |
| SCHEMBL27191847 | 0.73 | MAPT (0.34) | KDM4EALDH1A1MAPTNSD2MTNR1A | |
| SCHEMBL24163247 | 0.73 | MAPT (0.37) | KDM4EALDH1A1MAPTNSD2USP7 | |
| SCHEMBL26654555 | 0.72 | MTNR1A (0.32) | KDM4EALDH1A1MAPTNSD2USP7 | |
| SCHEMBL16060639 | 0.72 | MAPT (0.39) | DPP4DPP8KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660003-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-01-24 | — | — | EP | disclosed |