⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15900171 | 0.79 | — | — | |
| SCHEMBL3774083 | 0.77 | — | — | |
| SCHEMBL14909578 | 0.77 | USP2 (0.31) | — | |
| SCHEMBL16823316 | 0.76 | — | — | |
| SCHEMBL6294796 | 0.75 | — | — | |
| SCHEMBL17542612 | 0.74 | — | — | |
| SCHEMBL17074177 | 0.74 | — | — | |
| SCHEMBL15910747 | 0.72 | — | — | |
| SCHEMBL17363051 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL2868030 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119233974-A | Indolone derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| WO-2024017372-A1 | INDOLONE DERIVATIVE AND USE THEREOF | 成都百裕制药股份有限公司 | 2024-01-25 | — | — | WO | disclosed |