Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 19/20 | 0.55 |
| ▸ | OXTR | P30559 | 8/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.55 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702996 | 0.92 | AVPR1A (0.50) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2705085 | 0.92 | AVPR1A (0.56) | AVPR1AOXTRAVPR2TSPO | |
| SCHEMBL2704802 | 0.91 | AVPR1A (0.47) | AVPR1AOXTRAVPR2 | |
| SCHEMBL18917290 | 0.90 | AVPR1A (0.67) | AVPR1AOXTRAVPR2TSPO | |
| Cyclopropane SCHEMBL18917222 | 0.87 | AVPR1A (0.53) | AVPR1AOXTRAVPR2TSPO | |
| SCHEMBL2704077 | 0.86 | AVPR1A (0.55) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2131749 | 0.85 | AVPR1A (0.49) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2704236 | 0.83 | AVPR1A (0.51) | AVPR1AOXTRAVPR2TSPO | |
| SCHEMBL2704714 | 0.83 | AVPR1A (0.49) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2704240 | 0.82 | AVPR1A (0.52) | AVPR1AOXTRAVPR2TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | claimed |
| EP-2256119-B1 | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2012-05-09 | — | — | EP | claimed |