Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.47 |
| ▸ | OXTR | P30559 | 9/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704080 | 0.91 | AVPR1A (0.55) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2702996 | 0.90 | AVPR1A (0.50) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2705381 | 0.90 | AVPR1A (0.46) | AVPR1AOXTRAVPR2 | |
| SCHEMBL5549199 | 0.89 | AVPR1A (0.55) | AVPR1AOXTRAVPR2 | |
| Hydrochloric Acid SCHEMBL2131142 | 0.88 | AVPR1A (0.55) | AVPR1AOXTRAVPR2 | |
| Cyclopropane SCHEMBL18917240 | 0.87 | AVPR1A (0.46) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2704800 | 0.87 | AVPR1A (0.48) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2131383 | 0.86 | AVPR1A (0.43) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2705085 | 0.83 | AVPR1A (0.56) | AVPR1AOXTRAVPR2 | |
| SCHEMBL2704138 | 0.83 | AVPR1A (0.50) | AVPR1AOXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | claimed |
| EP-2256119-B1 | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2012-05-09 | — | — | EP | claimed |
| EP-1781661-A2 | VASOPRESSIN V1A ANTAGONISTS | Ferring B.V. (NL) | 2007-05-09 | — | — | EP | claimed |
| WO-2006021213-A2 | VASOPRESSIN V1A ANTAGONISTS | FERRING B.V. (NL) | 2006-03-02 | — | — | WO | claimed |