SCHEMBL27044633

SCHEMBL27044633

c1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccc8c9ccccc9c9ccccc9c8c7)c6ccc54)ccc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
KDM4E B2RXH2 2/20 0.58
ATM Q13315 1/20 0.58
JAK2 O60674 1/20 0.39
JAK3 P52333 1/20 0.39
MAPK1 P28482 1/20 0.38
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTPN1 P18031 2/20 0.35
MAPK8 P45983 2/20 0.35
IL1R1 P14778 1/20 0.35
HDAC4 P56524 1/20 0.35
PGR P06401 1/20 0.34
MAPK9 P45984 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16076357 0.97 L3MBTL1 (0.57) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL31337505 0.97 L3MBTL1 (0.57) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL24677369 0.95 L3MBTL1 (0.64) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17245449 0.95 L3MBTL1 (0.64) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL27427688 0.93 L3MBTL1 (0.62) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL27427683 0.93 L3MBTL1 (0.62) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL15073461 0.92 L3MBTL1 (0.60) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL15164562 0.92 L3MBTL1 (0.60) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL18126078 0.92 L3MBTL1 (0.64) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL19359874 0.92 KDM4E (0.47) L3MBTL1KDM4EATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032323-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240032323-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed