SCHEMBL27048383

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27047858	0.85	PLAU (0.56)	PLAUCYP2D6HTR7CYP3A4CYP2C19
	SCHEMBL27048636	0.85	PLAU (0.56)	PLAUALDH1A1GPR3HSD17B10HTT
	SCHEMBL27046291	0.81	PLAU (0.52)	PLAUCYP2D6HTR7CYP3A4CYP2C19
	SCHEMBL27047857	0.81	PLAU (0.56)	PLAUHTR7MAPTMEN1KMT2A
	SCHEMBL27048579	0.79	PLAU (0.54)	PLAUCYP2D6HTR7CYP3A4CYP2C19
	SCHEMBL27047949	0.79	PLAU (0.54)	PLAUHTR7ALDH1A1GPR3HSD17B10
	SCHEMBL27047922	0.78	PLAU (0.52)	PLAUHTR7ALDH1A1GPR3HSD17B10
	SCHEMBL27048655	0.78	PLAU (0.52)	PLAUCYP2D6HTR7CYP3A4CYP2C19
	SCHEMBL27047853	0.74	PLAU (0.49)	PLAUALDH1A1GPR3HSD17B10LMNA
	SCHEMBL17871279	0.74	CYP2D6 (0.46)	PLAUCYP2D6HTR7CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.