Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27048528 | 0.83 | LMNA (0.44) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL23602333 | 0.82 | LMNA (0.50) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL17525783 | 0.82 | LMNA (0.50) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL9807555 | 0.82 | LMNA (0.50) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL9231216 | 0.81 | LMNA (0.49) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL21473264 | 0.79 | LMNA (0.47) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL5956975 | 0.78 | LMNA (0.49) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL19125739 | 0.77 | LMNA (0.45) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL24393531 | 0.77 | LMNA (0.45) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 | |
| SCHEMBL23450919 | 0.75 | LMNA (0.50) | LMNAPOLBALDH1A1ANPEPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028021-B1 | USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF PAIN, AND CORRESPONDING COMPOSITIONS | NUVAMID SA (CH) | 2024-01-24 | — | — | EP | disclosed |