SCHEMBL2705415

SCHEMBL2705415

CCCCOc1ccc(OC(=O)CC)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
HIF1A Q16665 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
RECQL P46063 1/20 0.59
KMT2A Q03164 1/20 0.59
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
ELANE P08246 1/20 0.54
HTT P42858 1/20 0.54
NPC1 O15118 2/20 0.54
LMNA P02545 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
PLA2G4B P0C869 1/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6529326 0.98 ESR1 (0.58) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL9160861 0.95 TP53 (0.63) SMN1; SMN2TP53TSHRHTTNPC1
SCHEMBL7403966 0.92 KMT2A (0.59) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL17319274 0.90 RARB (0.66) SMN1; SMN2TP53TSHRHTTNPC1
SCHEMBL7668759 0.87 ESR1 (0.54) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL7484158 0.87 BCL9 (0.58) ESR1KMT2ATP53TSHRHTT
SCHEMBL11685017 0.87 SMN1; SMN2 (0.58) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL312147 0.85 KMT2A (0.76) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL26698279 0.85 KMT2A (0.56) ESR1HIF1ASMN1; SMN2RECQLKMT2A
SCHEMBL28653300 0.85 KMT2A (0.56) ESR1HIF1ASMN1; SMN2RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096420-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed
CN-110168065-A Low viscosity lubricating oil composition for turbomachinery 埃克森美孚研究工程公司 2019-08-23 CN disclosed
EP-2235106-B1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-11-21 EP disclosed
EP-2235105-B1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-13 EP disclosed
US-8168707-B2 Moldable polyester compositions, processes of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-01 US disclosed
EP-2235105-A1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2010-10-06 EP disclosed
EP-2235106-A1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2010-10-06 EP disclosed
WO-2009091818-A1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-23 WO disclosed
WO-2009091819-A1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-23 WO disclosed
US-20090181199-A1 MOLDABLE POLYESTER COMPOSITIONS, PROCESSES OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-16 US disclosed
US-5200477-A Having antiagglomerant inert particles with an organomodified polysiloxane present during the vapor phase polymerization to produce synthetic rubbers using a coordination catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-04-06 US disclosed