SCHEMBL2705948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2706617	0.87	MRGPRX4 (0.41)	MRGPRX4PARP1PDE10A
	SCHEMBL202543	0.82	GPBAR1 (0.48)	PDE10A
	SCHEMBL2704592	0.80	MRGPRX4 (0.41)	MRGPRX4PTGER1CYP1A2CYP2C9TBXA2R
	SCHEMBL2705947	0.79	MRGPRX4 (0.41)	MRGPRX4PTGER1CYP1A2CYP2C9TBXA2R
	SCHEMBL203022	0.79	NPC1 (0.43)	PDE10A
	SCHEMBL202189	0.78	MRGPRX4 (0.42)	MRGPRX4PTGER1CYP1A2CYP2C9TBXA2R
	SCHEMBL17274961	0.78	MRGPRX4 (0.42)	MRGPRX4PARP1PTGER1CYP1A2CYP2C9
	SCHEMBL2705641	0.75	BACE1 (0.36)	MRGPRX4PDE10A
	SCHEMBL2705627	0.75	MRGPRX4 (0.40)	MRGPRX4
	SCHEMBL2707218	0.75	CYSLTR1 (0.39)	MRGPRX4PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.