Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861572 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL4124188 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL10491008 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL22868105 | 0.85 | CA12 (0.46) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL4124134 | 0.85 | TSHR (0.47) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL4124137 | 0.85 | TSHR (0.47) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL2386329 | 0.83 | TSHR (0.46) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL6257260 | 0.83 | HIF1A (0.44) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL22950649 | 0.83 | TSHR (0.46) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 | |
| SCHEMBL5860329 | 0.83 | MEN1 (0.47) | ALDH1A1TSHRHSD17B10CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118891261-A | Covalent EGFR inhibitors and methods of use thereof | 丹娜-法伯癌症研究院 | 2024-11-01 | — | — | CN | disclosed |
| US-20240352021-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2024-10-24 | — | — | US | disclosed |
| CN-112300017-B | Racemization preparation method of chiral beta-amino acid and derivative thereof | 浙江九洲药业股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023069959-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| CN-112300017-A | Racemization preparation method of chiral beta-amino acid and derivative thereof | 浙江九洲药业股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| EP-2492275-B1 | NOVEL RUTHENIUM CARBONYL COMPLEX HAVING A TRIDENTATE LIGAND AND MANUFACTURING METHOD AND USAGE THEREFOR | TAKASAGO PERFUMERY CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-1970360-B1 | Method for producing alcohols | TAKASAGO PERFUMERY CO LTD (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-2492275-A1 | NOVEL RUTHENIUM CARBONYL COMPLEX HAVING A TRIDENTATE LIGAND AND MANUFACTURING METHOD AND USAGE THEREFOR | Takasago International Corporation (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2450358-A1 | Fused, tricyclic sulfonamide inhibitors of gamma secretase | Elan Pharmaceuticals Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| US-7709471-B2 | Compounds | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-5696130-A | Tricyclic steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-09 | — | — | US | disclosed |
| US-5696133-A | ADMINISTERING COMPOUND WHICH MODULATES ACTIVITY OF PROGESTERONE RECEPTOR | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-09 | — | — | US | disclosed |
| US-5693646-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
| US-5693647-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
| US-5688808-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-11-18 | — | — | US | disclosed |
| US-5688810-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0800519-A1 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019458-A2 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-06-27 | — | — | WO | disclosed |
| EP-0226584-A1 | GAS SENSORS, AND METHODS OF MAKING AND USING THEM | Cogent Limited (GB) | 1987-07-01 | — | — | EP | disclosed |
| WO-1986001599-A1 | GAS SENSORS, AND METHODS OF MAKING AND USING THEM | COGENT LIMITED (GB) | 1986-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352021-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | EGFR, ERBB2, ERBB3 | ALDH1A1 2865/4885TSHR 966/4885HSD17B10 3418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.