Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 12/20 | 0.69 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24850604 | 0.91 | IKZF2 (0.73) | IKZF2IKZF1CRBN | |
| SCHEMBL23105167 | 0.89 | IKZF2 (0.69) | IKZF2IKZF1CRBN | |
| SCHEMBL24530849 | 0.88 | IKZF2 (0.65) | IKZF2IKZF1CRBN | |
| SCHEMBL26610511 | 0.87 | IKZF2 (0.66) | IKZF2IKZF1CRBN | |
| SCHEMBL26609674 | 0.87 | IKZF2 (0.69) | IKZF2IKZF1CRBN | |
| SCHEMBL26609378 | 0.86 | IKZF2 (0.68) | IKZF2IKZF1CRBN | |
| SCHEMBL26609347 | 0.86 | IKZF2 (0.67) | IKZF2IKZF1CRBN | |
| SCHEMBL23710977 | 0.86 | IKZF2 (0.62) | IKZF2IKZF1CRBN | |
| SCHEMBL25079657 | 0.86 | IKZF2 (0.64) | IKZF2IKZF1CRBN | |
| SCHEMBL25010615 | 0.85 | IKZF2 (0.69) | IKZF2IKZF1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025863-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025863-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | SOS1, SOS2, SOST | IKZF2 2621/4885IKZF1 1510/4885CRBN 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.