Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431449 | 0.89 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL432661 | 0.88 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL433133 | 0.88 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL432662 | 0.88 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL431772 | 0.81 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL430343 | 0.81 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL427922 | 0.75 | LMNA (0.50) | TRPV1 | |
| SCHEMBL430316 | 0.75 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL431471 | 0.74 | MAPT (0.53) | TRPV1 | |
| SCHEMBL430388 | 0.73 | TRPV1 (0.58) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450346-A1 | Antagonists of the TRPV1 receptor and uses thereof | Abbott Laboratories (US) | 2012-05-09 | — | — | EP | disclosed |