Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 3/20 | 0.41 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATG7 | O95352 | 1/20 | 0.38 |
| ▸ | NADK | O95544 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215196 | 0.87 | ADORA3 (0.67) | ADORA2AADORA3TRPM2HSPA5SLC28A2 | |
| SCHEMBL29673048 | 0.87 | ADORA3 (0.67) | ADORA2AADORA3TRPM2HSPA5SLC28A2 | |
| SCHEMBL29283549 | 0.87 | ADORA3 (0.67) | ADORA2AADORA3TRPM2HSPA5SLC28A2 | |
| SCHEMBL23240747 | 0.87 | ADORA3 (0.67) | ADORA2AADORA3TRPM2HSPA5SLC28A2 | |
| SCHEMBL29283548 | 0.87 | ADORA3 (0.67) | ADORA2AADORA3TRPM2HSPA5SLC28A2 | |
| SCHEMBL14253676 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3TRPM2ADORA2BHSPA5 | |
| SCHEMBL29673055 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3TRPM2ADORA2BHSPA5 | |
| SCHEMBL24420987 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3TRPM2ADORA2BHSPA5 | |
| SCHEMBL659995 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3TRPM2ADORA2BHSPA5 | |
| SCHEMBL440599 | 0.80 | ADORA2A (0.64) | ADORA2AADORA3TRPM2ADORA2BHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |