Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.80 |
| ▸ | FKBP5 | Q13451 | 6/20 | 0.72 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.72 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15597349 | 1.00 | FKBP1A (0.80) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL25737407 | 0.93 | FKBP1A (0.70) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL24685955 | 0.92 | FKBP1A (0.81) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL16975607 | 0.92 | FKBP1A (0.91) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL22221420 | 0.90 | FKBP1A (0.75) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL17172729 | 0.90 | FKBP1A (0.80) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL25737452 | 0.89 | FKBP1A (0.72) | FKBP1AFKBP5FKBP1BFKBP4 | |
| SCHEMBL20791944 | 0.89 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL16809378 | 0.89 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 | |
| SCHEMBL22451751 | 0.89 | FKBP1A (1.00) | FKBP1AFKBP5FKBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2024-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024490-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | FKBP1A 1249/4885FKBP5 1235/4885FKBP1B 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.