SCHEMBL2706447

SCHEMBL2706447

O=C(OCc1ccccc1)c1ccccn1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.71
NPSR1 Q6W5P4 2/20 0.67
POLB P06746 1/20 0.59
TDP1 Q9NUW8 3/20 0.58
KMT2A Q03164 2/20 0.58
SLC6A2 P23975 1/20 0.58
SLC6A3 Q01959 1/20 0.58
L3MBTL1 Q9Y468 7/20 0.55
TSHR P16473 3/20 0.55
CASP3 P42574 1/20 0.55
RAB9A P51151 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
ALDH1A1 P00352 5/20 0.55
ALOX15 P16050 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 3/20 0.54
NAPRT Q6XQN6 1/20 0.53
P4HTM Q9NXG6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30711263 1.00 PKM (0.71) PKMNPSR1POLBTDP1KMT2A
Hydrochloric Acid SCHEMBL28329265 0.98 PKM (0.69) PKMNPSR1POLBTDP1KMT2A
SCHEMBL1551668 0.98 PKM (0.69) PKMNPSR1POLBTDP1KMT2A
SCHEMBL28289255 0.87 PKM (0.68) PKMNPSR1POLBTDP1KMT2A
SCHEMBL27684585 0.86 PKM (0.56) PKMNPSR1POLBKMT2AL3MBTL1
SCHEMBL29179234 0.85 PKM (0.54) PKMNPSR1POLBKMT2AL3MBTL1
SCHEMBL27945708 0.85 PKM (0.73) PKMNPSR1POLBKMT2AL3MBTL1
Ethyl Picolinate SCHEMBL7863824 0.84 PKM (0.64) PKMNPSR1POLBTDP1KMT2A
SCHEMBL28330547 0.84 NPSR1 (0.64) PKMNPSR1POLBKMT2AL3MBTL1
SCHEMBL27665138 0.83 ESR1 (0.54) PKMNPSR1TDP1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112725852-B Alkaline zinc-nickel alloy electroplating solution and preparation method and electroplating process thereof 杭州佳兴镀锌有限公司 2022-03-25 CN claimed
CN-112725852-A Alkaline zinc-nickel alloy electroplating solution and preparation method and electroplating process thereof 杭州佳兴镀锌有限公司 2021-04-30 CN claimed
CN-109561682-A Pyridine compounds and their comprising isoxazoline ring and its purposes as herbicide 牧牛研究所株式会社 2019-04-02 CN claimed
CN-1072222-C Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings UPJOHN CO (US) 2001-10-03 CN claimed
WO-2001019185-A2 METHODS FOR CONTROLLING A PEST POPULATION SUMMUS GROUP, LTD. (US) 2001-03-22 WO claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
CN-1197457-A Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring UPJOHN CO (US) 1998-10-28 CN claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US claimed
CN-119301127-A 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions 瑞克鲁迪克斯制药股份有限公司 2025-01-10 CN disclosed
CN-117794526-A Compositions and methods for antioxidants and anti-inflammatory therapeutics 阿万蒂生物科学股份有限公司 2024-03-29 CN disclosed
CN-117769554-A Small molecule inhibitors of KRAS muteins 大鹏药品工业株式会社 2024-03-26 CN disclosed
CN-117242056-A Novel compounds useful as STING agonists and uses thereof 北京加科思新药研发有限公司 2023-12-15 CN disclosed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed
CN-1126203-A Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals HOECHST AG (DE) 1996-07-10 CN disclosed
CN-1107476-A Heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-08-30 CN disclosed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US disclosed