⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27041435 | 0.93 | CBLB (0.36) | — | |
| SCHEMBL27068119 | 0.85 | CBLB (0.40) | — | |
| SCHEMBL27068278 | 0.82 | CBLB (0.35) | — | |
| SCHEMBL30728175 | 0.81 | CBLB (0.39) | — | |
| SCHEMBL27068276 | 0.81 | CBLB (0.39) | — | |
| SCHEMBL27068273 | 0.80 | BRD4 (0.32) | — | |
| SCHEMBL27068170 | 0.80 | CBLB (0.40) | — | |
| SCHEMBL30728232 | 0.80 | CBLB (0.48) | — | |
| SCHEMBL27068275 | 0.79 | BRD4 (0.32) | — | |
| SCHEMBL27068115 | 0.79 | CBLB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |