Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32666905 | 0.92 | CBLB (0.37) | BRD4 | |
| SCHEMBL27068275 | 0.91 | BRD4 (0.32) | BRD4 | |
| SCHEMBL27068274 | 0.83 | — | — | |
| SCHEMBL32666859 | 0.81 | CBLB (0.35) | BRD4 | |
| SCHEMBL27068272 | 0.80 | — | — | |
| SCHEMBL27068119 | 0.80 | CBLB (0.40) | BRD4 | |
| SCHEMBL30999266 | 0.76 | CBLB (0.51) | — | |
| SCHEMBL27068277 | 0.76 | BRD4 (0.36) | BRD4 | |
| SCHEMBL27068116 | 0.75 | CBLB (0.51) | — | |
| SCHEMBL27068279 | 0.75 | CBLB (0.38) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |