SCHEMBL27068340

SCHEMBL27068340

O=c1c2[nH]c(CN3CCCCC3)cc2c(C2CC2)cn1-c1cccc(C2(c3nncn3C3CC3)CC3(CC3)C2)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 2/20 0.30
▸ CBL P22681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30728195 0.92 CBLB (0.39) CBLBCBL
SCHEMBL27068115 0.91 CBLB (0.39) CBLBCBL
SCHEMBL27068341 0.89 CBLB (0.31) CBLBCBL
SCHEMBL27068378 0.88 CBLB (0.33) CBLBCBL
SCHEMBL27068119 0.84 CBLB (0.40) CBLBCBL
SCHEMBL27068111 0.84 CBLB (0.39) CBLBCBL
SCHEMBL30728164 0.84 CBLB (0.47) CBLBCBL
SCHEMBL27068109 0.83 CBLB (0.39) CBLBCBL
SCHEMBL27067893 0.82 CBLB (0.49) CBLBCBL
SCHEMBL27067894 0.82 CBLB (0.49) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024020034-A1 CBL-B INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2024-01-25 — — WO disclosed
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