Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67163 | 0.85 | CYP2B6 (0.55) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL5305394 | 0.82 | CYP2B6 (0.55) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL8818968 | 0.81 | CHRM2 (0.43) | CYP2B6CHRM2CHRM1LMNACHRM3 | |
| SCHEMBL11542596 | 0.81 | CYP2B6 (0.53) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL5051404 | 0.78 | CYP2B6 (0.50) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL5290364 | 0.78 | CYP2B6 (0.50) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL7547849 | 0.78 | CYP2B6 (0.55) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL8634062 | 0.77 | NPC1 (0.37) | CYP2B6CYP2D6CHRM1CHRM3KDM4E | |
| SCHEMBL5302731 | 0.77 | CYP2B6 (0.58) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL597167 | 0.76 | CYP2B6 (0.52) | CYP2B6CYP2D6CHRM2CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289697-B | Scoring balloon with translating score line | 巴德股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-114795402-A | Scoring balloon with translating score line | 巴德股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-2125038-B1 | RADIOACTIVE PET AGENTS FOR IMAGING CCR5 IN VIVO | GE HEALTHCARE LTD (GB) | 2012-05-02 | — | — | EP | disclosed |
| EP-2125038-A2 | RADIOACTIVE PET AGENTS FOR IMAGING CCR5 IN VIVO | GE Healthcare Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008075040-A2 | IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |