Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013935 | 1.00 | CYP2B6 (0.52) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| Hydrochloric Acid SCHEMBL8017738 | 0.98 | CYP2B6 (0.50) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL7547849 | 0.98 | CYP2B6 (0.55) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL4541997 | 0.84 | KCNA5 (0.48) | OPRM1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9816209 | 0.84 | CHRM2 (0.48) | CYP2D6CHRM2CHRM1HTR1AOPRM1 | |
| SCHEMBL9366900 | 0.79 | CYP2B6 (0.49) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL5305394 | 0.77 | CYP2B6 (0.55) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL14354381 | 0.76 | CYP2B6 (0.39) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL5302731 | 0.76 | CYP2B6 (0.58) | CYP2B6CYP2D6CHRM2CHRM1HTR1A | |
| SCHEMBL2707429 | 0.76 | CYP2B6 (0.58) | CYP2B6CYP2D6CHRM2CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417096-B1 | Process for the synthesis of a propargylic alcohol | LONZA AG (CH) | 2013-01-16 | — | — | EP | disclosed |
| US-8283502-B2 | Autocatalytic process for the synthesis of chiral propargylic alcohols | LONZA LTD. (CH) | 2012-10-09 | — | — | US | disclosed |
| US-8115032-B2 | Process for the synthesis of a propargylic alcohol | LONZA LTD. (CH) | 2012-02-14 | — | — | US | disclosed |
| US-20110172464-A1 | PROCESS FOR THE SYNTHESIS OF A PROPARGYLIC ALCOHOL | LONZA LTD. (CH) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172464-A1 | PROCESS FOR THE SYNTHESIS OF A PROPARGYLIC ALCOHOL | ADH1A, ADH1C, ADH5 | CYP2B6 59/4885CYP2D6 128/4885CHRM2 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.