Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 17/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27081043 | 0.96 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL29983878 | 0.93 | CD274 (0.40) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27079293 | 0.91 | CD274 (0.48) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836458 | 0.90 | CD274 (0.53) | CD274PDCD1 | |
| SCHEMBL29983642 | 0.90 | CD274 (0.43) | CD274PDCD1 | |
| SCHEMBL29982764 | 0.89 | CD274 (0.51) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27078713 | 0.89 | CD274 (0.51) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL27081086 | 0.87 | PDCD1 (0.54) | CD274PDCD1 | |
| SCHEMBL27079039 | 0.86 | CD274 (0.51) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL29143902 | 0.86 | CD274 (0.48) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313968-A2 | SUBSTITUTED 1-ARYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1,1'-BIHETEROARYL COMPOUNDS, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2024-02-07 | — | — | EP | disclosed |