Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086659 | 0.91 | GPR119 (0.55) | GPR119KCNH2FAAH | |
| SCHEMBL30001907 | 0.91 | GPR119 (0.55) | GPR119KCNH2FAAH | |
| SCHEMBL1922598 | 0.87 | GPR119 (0.71) | GPR119KCNH2 | |
| SCHEMBL1575319 | 0.86 | GPR119 (0.66) | GPR119FAAH | |
| SCHEMBL1575092 | 0.83 | GPR119 (0.58) | GPR119FAAH | |
| SCHEMBL1575436 | 0.83 | GPR119 (0.78) | GPR119FAAH | |
| SCHEMBL1922356 | 0.83 | GPR119 (0.64) | GPR119FAAH | |
| SCHEMBL1576052 | 0.83 | GPR119 (0.79) | GPR119 | |
| SCHEMBL1575946 | 0.82 | GPR119 (0.68) | GPR119FAAH | |
| SCHEMBL1575154 | 0.82 | GPR119 (0.57) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320129-A1 | GPR119 AGONISTS | Kallyope, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216709-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |