Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27089326 | 1.00 | DPP4 (0.33) | DPP4DPP8DPP7OPRM1OPRK1 | |
| SCHEMBL16300657 | 0.86 | DPP4 (0.34) | DPP4DPP8DPP7OPRM1OPRK1 | |
| SCHEMBL3512916 | 0.84 | GRM2 (0.36) | DPP4 | |
| SCHEMBL6919995 | 0.84 | GRM2 (0.36) | DPP4 | |
| SCHEMBL4254372 | 0.84 | GRM2 (0.36) | DPP4 | |
| SCHEMBL2845977 | 0.81 | CNR2 (0.41) | OPRM1OPRK1 | |
| SCHEMBL15129890 | 0.81 | CNR2 (0.41) | OPRM1OPRK1 | |
| SCHEMBL28038908 | 0.81 | CNR2 (0.41) | OPRM1OPRK1 | |
| SCHEMBL17867671 | 0.80 | ENPP2 (0.36) | DPP4DPP8DPP7OPRM1OPRK1 | |
| SCHEMBL3012517 | 0.80 | PEPD (0.39) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117083279-A | Oxazepine compounds and their use in the treatment of cancer | 基因泰克公司 | 2023-11-17 | — | — | CN | disclosed |