Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXK | P42681 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23365946 | 0.92 | CA12 (0.58) | TXKJAK3BTKCA12CA1 | |
| SCHEMBL27089672 | 0.86 | PRSS1 (0.49) | TXKJAK3BTKFOLH1NOXO1 | |
| SCHEMBL20161403 | 0.84 | CA12 (0.60) | TXKJAK3BTKCA12CA1 | |
| SCHEMBL23365942 | 0.82 | CA12 (0.58) | TXKJAK3BTKCA12CA1 | |
| SCHEMBL26553927 | 0.79 | PRSS1 (0.56) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL26554090 | 0.78 | PRSS1 (0.59) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL26553921 | 0.78 | PRSS1 (0.59) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL23365916 | 0.78 | F2 (0.60) | FOLH1NOXO1PRSS1PRSS2PRSS3 | |
| SCHEMBL20161540 | 0.77 | F2 (0.62) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL12028695 | 0.76 | PRSS1 (0.62) | CA12CA1CA2CA9FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897874-B2 | Compounds and methods for modulating Interleukin-2-inducible T-cell kinase | CORVUS PHARMACEUTICALS, INC. (US) | 2024-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897874-B2 | Compounds and methods for modulating Interleukin-2-inducible T-cell kinase | IL2, NFATC1, IL2RA | TXK 201/4885JAK3 341/4885BTK 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.