Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140318 | 1.00 | POLB (0.48) | POLBSYKALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20272638 | 0.84 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL30863382 | 0.81 | ABCB1 (0.49) | POLBSYKALDH1A1SMN1; SMN2 | |
| SCHEMBL30878162 | 0.81 | POLB (0.47) | POLBSYKALDH1A1SMN1; SMN2 | |
| SCHEMBL19456479 | 0.81 | POLB (0.47) | POLBSYKALDH1A1SMN1; SMN2NTSR1 | |
| SCHEMBL30307663 | 0.81 | POLB (0.47) | POLBSYKALDH1A1SMN1; SMN2 | |
| SCHEMBL2499502 | 0.81 | POLB (0.47) | POLBSYKALDH1A1SMN1; SMN2 | |
| SCHEMBL2136696 | 0.81 | POLB (0.46) | POLBSYKALDH1A1GAANTSR1 | |
| SCHEMBL2138277 | 0.81 | POLB (0.46) | POLBSYKALDH1A1GAANTSR1 | |
| SCHEMBL12345526 | 0.80 | ALDH1A1 (0.51) | POLBSYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |