⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515022 | 0.59 | — | — | |
| SCHEMBL785169 | 0.59 | — | — | |
| SCHEMBL118393 | 0.59 | — | — | |
| SCHEMBL28667 | 0.59 | — | — | |
| SCHEMBL22284113 | 0.59 | ALDH1A1 (1.00) | — | |
| SCHEMBL11820516 | 0.59 | — | — | |
| Acrylonitrile SCHEMBL16594932 | 0.56 | — | — | |
| SCHEMBL200596 | 0.56 | — | — | |
| Water SCHEMBL7486682 | 0.56 | — | — | |
| Acrylonitrile SCHEMBL22582794 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149214-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS-12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | claimed |
| WO-2024138486-A1 | TETRACYCLIC DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| EP-4370522-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | Nikang Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | claimed |
| CN-117980310-A | Alkylene derivatives as KRAS inhibitors | 尼坎治疗公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2024054625-A2 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | claimed |
| WO-2024045066-A1 | ALKYLIDENE CARBAMATE AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | claimed |
| WO-2024046406-A1 | ALKYLIDENE CARBAMATE AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | claimed |
| WO-2023239846-A1 | HETEROCYCLIC COMPOUNDS AS PI3KΑ INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | claimed |
| US-11788138-B2 | Nucleic acid sequencing using affinity reagents | MGI TECH CO., LTD. (CN) | 2023-10-17 | — | — | US | claimed |
| US-20230229077-A1 | PHOTOACID GENERATOR FOR CHEMICALLY AMPLIFIED PHOTORESISTS FOR DEEP ULTRAVIOLET AND EXTREME ULTRAVIOLET LITHOGRAPHY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2023-07-20 | — | — | US | claimed |
| EP-0099017-B1 | PHENYL-ACETIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSTIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1988-03-02 | — | — | EP | claimed |
| EP-0257828-A1 | Dipropargyloxybenzene compounds and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-02 | — | — | EP | claimed |
| EP-0208200-A1 | Phenylacetic-acid derivatives, pharmaceutical compositions containing them and processes for their production | Dr. Karl Thomae GmbH (DE) | 1987-01-14 | — | — | EP | claimed |
| EP-0063905-B1 | FUNGICIDAL N-PHENYLCARBAMATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-14 | — | — | EP | claimed |
| US-4482546-A | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | claimed |
| EP-0018473-B1 | PROCESS FOR THE PREPARATION OF BETA-ALKOXY-ACRYLONITRILES, 3-AMINO-ACRYLONITRILES AND 2-CYANO-VINYL ESTERS | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | claimed |
| EP-0063905-A1 | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-11-03 | — | — | EP | claimed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| US-4105653-A | HETERYL-AZO-PHENYL DISPERSE DYESTUFFS CONTAINING A Z-SUBSTITUTED BENZOLYLOXYALKYL RADICAL, WHEREIN Z IS 2-CYANOVINYL 2-CYANOETHYL OR 2-CHLORO-2-CYANOETHYL | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-08-08 | — | — | US | claimed |
| US-3987027-A | DISPERSE AZO DYES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-10-19 | — | — | US | claimed |