Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.44 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | WIZ | O95785 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985233 | 0.96 | CRBN (0.52) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL20234853 | 0.96 | CRBN (0.52) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL31727669 | 0.96 | CRBN (0.52) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL30984991 | 0.94 | CRBN (0.51) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL31726811 | 0.92 | CRBN (0.52) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL22498388 | 0.92 | CRBN (0.52) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL30984958 | 0.91 | CRBN (0.51) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL30942480 | 0.90 | CRBN (0.54) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL20231913 | 0.90 | CRBN (0.54) | CRBNCSNK1A1DDB1IKZF2GSPT1 | |
| SCHEMBL30942469 | 0.90 | CRBN (0.47) | CRBNCSNK1A1DDB1IKZF2GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388454-A | Modulators of BCL6 proteolysis and related methods of use | 阿尔维纳斯运营股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |