Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.51 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.45 |
| ▸ | WIZ | O95785 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24571664 | 0.96 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL30984991 | 0.95 | CRBN (0.51) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL31726811 | 0.95 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL22498388 | 0.95 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL31727669 | 0.93 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL20234853 | 0.93 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL30985233 | 0.93 | CRBN (0.52) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL27092903 | 0.91 | CRBN (0.49) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL20231913 | 0.90 | CRBN (0.54) | CRBNIKZF2CSNK1A1DDB1WIZ | |
| SCHEMBL30942480 | 0.90 | CRBN (0.54) | CRBNIKZF2CSNK1A1DDB1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709486-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Celgene Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233748-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | CELGENE CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |