SCHEMBL27092958

SCHEMBL27092958

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DOT1L Q8TEK3 6/20 0.82
EHMT2 Q96KQ7 4/20 0.82
NNMT P40261 4/20 0.82
CARM1 Q86X55 3/20 0.82
NSD2 O96028 3/20 0.82
SETD7 Q8WTS6 3/20 0.82
PNMT P11086 2/20 0.82
DNMT1 P26358 2/20 0.82
DNMT3B Q9UBC3 2/20 0.82
TRDMT1 O14717 2/20 0.82
PRMT5 O14744 2/20 0.82
INMT O95050 2/20 0.82
METTL3 Q86U44 2/20 0.82
PRMT1 Q99873 2/20 0.82
EHMT1 Q9H9B1 2/20 0.82
METTL14 Q9HCE5 2/20 0.82
SUV39H1 O43463 1/20 0.82
PRMT3 O60678 1/20 0.82
HNMT P50135 1/20 0.82
WDR5 P61964 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27092961 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
SCHEMBL19433776 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
SCHEMBL19433014 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
SCHEMBL95173 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
SCHEMBL19433069 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
SCHEMBL18661551 1.00 DOT1L (0.82) DOT1LEHMT2NNMTCARM1NSD2
S-Adenosylhomocysteine SCHEMBL13033864 0.90 DOT1L (1.00) DOT1LEHMT2NNMTCARM1NSD2
S-Adenosylhomocysteine SCHEMBL18826562 0.90 DOT1L (1.00) DOT1LEHMT2NNMTCARM1NSD2
S-Adenosylhomocysteine SCHEMBL14434697 0.90 DOT1L (1.00) DOT1LEHMT2NNMTCARM1NSD2
S-Adenosylhomocysteine SCHEMBL21160481 0.90 DOT1L (1.00) DOT1LEHMT2NNMTCARM1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116716332-B Application of recombinant saccharomyces cerevisiae in production of homoeriodictyol by using p-coumaric acid 天津大学合成生物前沿研究院 2025-06-17 CN claimed
EP-4324928-A1 SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION Universität Basel (CH) 2024-02-21 EP claimed
CN-116716332-A Application of recombinant saccharomyces cerevisiae in production of homoeriodictyol by using p-coumaric acid 天津大学合成生物前沿研究院 2023-09-08 CN claimed
CN-116716332-B Application of recombinant saccharomyces cerevisiae in production of homoeriodictyol by using p-coumaric acid 天津大学合成生物前沿研究院 2025-06-17 CN disclosed
CN-119082239-A Application of recombinant saccharomyces cerevisiae in production of eriodictyol 7-O-glucoside by utilizing glucose 蓝海新材料(通州湾)有限责任公司 2024-12-06 CN disclosed
CN-118910118-A Application of recombinant saccharomyces cerevisiae in de novo synthesis of eriodictyol by utilizing glucose 天津大学合成生物前沿研究院 2024-11-08 CN disclosed
EP-4324928-A1 SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION Universität Basel (CH) 2024-02-21 EP disclosed
CN-116716332-A Application of recombinant saccharomyces cerevisiae in production of homoeriodictyol by using p-coumaric acid 天津大学合成生物前沿研究院 2023-09-08 CN disclosed