SCHEMBL2709332

SCHEMBL2709332

C=C(C(=O)OC(C)C)C(=O)OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ADRA1A P35348 1/20 0.41
PDE4D Q08499 1/20 0.41
HCAR2 Q8TDS4 1/20 0.37
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA12 O43570 6/20 0.33
CA1 P00915 6/20 0.33
CA2 P00918 6/20 0.33
CA9 Q16790 6/20 0.33
CA7 P43166 4/20 0.33
CA14 Q9ULX7 4/20 0.33
LMNA P02545 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11703818 0.87 TSHR (0.42) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL6290792 0.87 TSHR (0.48) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL19687702 0.84 ALDH1A1 (0.44) TSHRGAASMN1; SMN2LMNAALDH1A1
SCHEMBL16128812 0.81 TSHR (0.37) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL14095566 0.81 TSHR (0.37) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL297916 0.81 TSHR (0.59) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL15253 0.80
SCHEMBL9372154 0.80
SCHEMBL21772350 0.80 TSHR (0.52) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL1003135 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999866-B2 Polymalonate and cyanoacrylate based surface concrete sealers ZEPHYROS, INC. (US) 2024-06-04 US claimed
EP-3515994-B1 METHOD FOR SEALING POROUS SUBSTRATES ZEPHYROS INC (US) 2024-01-24 EP claimed
WO-2021231288-A1 IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS NIPPON SHOKUBAI CO., LTD. (JP) 2021-11-18 WO claimed
US-20210324227-A1 Polymalonate and Cyanoacrylate Based Surface Concrete Sealers ZEPHYROS, INC. 2021-10-21 US claimed
WO-2021162938-A1 COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM SIRRUS, INC. (US) 2021-08-19 WO claimed
EP-3789408-A1 SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS Sirrus, Inc. (US) 2021-03-10 EP claimed
CN-111825785-A Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds 赛鲁斯股份有限公司 2020-10-27 CN claimed
CN-107075223-B Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds 赛鲁斯股份有限公司 2020-08-04 CN claimed
EP-3191546-B1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS INC (US) 2020-07-22 EP claimed
EP-3683267-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS Sirrus, Inc. (US) 2020-07-22 EP claimed
US-20170240657-A1 SOLUTION POLYMERS FORMED FROM METHYLENE MALONATE MONOMERS, POLYMERIZATION, AND SOLUTION POLYMER PRODUCTS SIRRUS, INC. 2017-08-24 US claimed
US-20170198181-A1 EMULSION INCLUDING POLYMERS CONTAINING A 1,1-DISUBSTITUTED ALKENE COMPOUND, ADHESIVES, COATINGS, AND METHODS THEREOF NIPPON SHOKUBAI CO., LTD. (JP) 2017-07-13 US claimed
US-20170190807-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. 2017-07-06 US claimed
US-9676875-B2 Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions SIRRUS, INC. (US) 2017-06-13 US claimed
US-9637564-B2 Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions SIRRUS, INC. (US) 2017-05-02 US claimed
US-20160096907-A1 EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. 2016-04-07 US claimed
US-20160096906-A1 SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS NIPPON SHOKUBAI CO., LTD. (JP) 2016-04-07 US claimed
US-20160068616-A1 SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS SIRRUS, INC. 2016-03-10 US claimed
US-9279022-B1 Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions SIRRUS, INC. (US) 2016-03-08 US claimed
US-9234107-B2 Ink coating formulations and polymerizable systems for producing the same SIRRUS, INC. (US) 2016-01-12 US claimed