Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263643 | 1.00 | TDP1 (0.58) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL29381867 | 1.00 | TDP1 (0.58) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL28707214 | 1.00 | TDP1 (0.58) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL6150030 | 0.85 | GLS (0.55) | TDP1L3MBTL1CYP1A2CYP2C19ACHE | |
| SCHEMBL8862878 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL2604742 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL6777483 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8862728 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8863154 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 | |
| SCHEMBL8863094 | 0.85 | TDP1 (0.75) | TDP1L3MBTL1CHRM2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
| EP-4323348-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | Studiengesellschaft Kohle gGmbH (DE) | 2024-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | CYP4F3, GTF3C3, GTF3C4 | TDP1 3277/4885L3MBTL1 4364/4885CHRM2 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.