Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24084089 | 0.94 | MDM4 (0.51) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL31133584 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL30779239 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL20732316 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL22069879 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL22069859 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL20732318 | 0.92 | PTPN1 (0.49) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL25845385 | 0.90 | TLR2 (0.54) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL23447188 | 0.90 | TLR2 (0.56) | TLR2MDM4TP53MDM2KMT2A | |
| SCHEMBL21837757 | 0.90 | TLR2 (0.49) | TLR2MDM4TP53MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666787-B1 | ANTIBODY-DRUG CONJUGATES INCLUDING HEMIASTERLIN DERIVATIVE | SUMITOMO PHARMA CO LTD (JP) | 2024-02-21 | — | — | EP | disclosed |