Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206301 | 0.92 | P2RX3 (0.81) | P2RX3P2RX2 | |
| SCHEMBL311221 | 0.84 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL310823 | 0.82 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL310920 | 0.82 | P2RX3 (0.77) | P2RX3P2RX2 | |
| SCHEMBL311216 | 0.82 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL310360 | 0.82 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL312096 | 0.82 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL310997 | 0.81 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL310444 | 0.81 | P2RX3 (1.00) | P2RX3P2RX2 | |
| SCHEMBL2710320 | 0.80 | P2RX3 (0.71) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445889-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-05-02 | — | — | EP | claimed |
| WO-2010149541-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-29 | — | — | WO | claimed |
| EP-2445889-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149541-A1 | NOVEL OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-29 | — | — | WO | disclosed |