Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 17/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907074 | 0.90 | TYMP (0.38) | TYMPFFAR4ACHE | |
| SCHEMBL25031006 | 0.87 | TYMP (0.39) | TYMPFFAR4 | |
| SCHEMBL27098837 | 0.84 | FFAR4 (0.41) | TYMPFFAR4ACHE | |
| SCHEMBL27098839 | 0.79 | CSF1R (0.40) | FFAR4ACHE | |
| SCHEMBL27098834 | 0.77 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL19511115 | 0.76 | FFAR4 (0.48) | FFAR4 | |
| SCHEMBL22907071 | 0.76 | PIK3CA (0.36) | FFAR4ACHE | |
| SCHEMBL19511018 | 0.75 | FFAR4 (0.47) | FFAR4 | |
| SCHEMBL27098833 | 0.74 | FFAR4 (0.38) | FFAR4 | |
| SCHEMBL19511081 | 0.73 | FFAR4 (0.48) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | TYMP 3017/4885FFAR4 4727/4885ACHE 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.