Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098837 | 0.90 | FFAR4 (0.41) | ALOX5APFEN1FFAR4ACHE | |
| SCHEMBL22907074 | 0.84 | TYMP (0.38) | FFAR4ACHEAKR1C3 | |
| SCHEMBL25031021 | 0.78 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL20648809 | 0.76 | WEE1 (0.38) | ALOX5APFEN1 | |
| SCHEMBL29776131 | 0.76 | WEE1 (0.38) | ALOX5APFEN1 | |
| SCHEMBL27098835 | 0.76 | TYMP (0.42) | FFAR4ACHE | |
| SCHEMBL25194061 | 0.75 | FFAR4 (0.39) | FFAR4 | |
| SCHEMBL28995474 | 0.74 | FFAR4 (0.56) | FFAR4 | |
| SCHEMBL20648918 | 0.73 | MAPT (0.47) | — | |
| SCHEMBL29506613 | 0.73 | MAPT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011913-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-01-21 | — | — | WO | disclosed |