Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | AANAT | Q16613 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27099051 | 0.99 | MTNR1A (0.82) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL27099044 | 0.91 | MTNR1A (0.77) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL29926356 | 0.90 | MTNR1A (0.98) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL6646410 | 0.90 | MTNR1A (0.88) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL1727281 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL3806536 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL1066221 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL1724741 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL22411433 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER | |
| SCHEMBL1725354 | 0.89 | MTNR1A (1.00) | MTNR1AMEN1KMT2AMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912687-B2 | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof | Board of Trustees of the Southern Illinois University (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912687-B2 | 3,4,5-trisubstituted-1,2,4-triazoles and 3,4,5-trisubstituted-3-thio-1,2,4-triazoles and uses thereof | SSTR4, SSTR5, SSTR3 | MTNR1A 178/4885MEN1 1253/4885KMT2A 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.