SCHEMBL27100749

SCHEMBL27100749

CC1(C)c2cc(C(=O)c3ccccc3)ccc2NC12C=Cc1cc([N+](=O)[O-])ccc1O2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
GFER P55789 1/20 0.47
MAPK1 P28482 2/20 0.37
POLB P06746 1/20 0.37
TDP2 O95551 2/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HIF1A Q16665 1/20 0.36
EPAS1 Q99814 1/20 0.36
LMNA P02545 3/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
GAA P10253 1/20 0.36
VCAM1 P19320 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27100756 0.96 MEN1 (0.51) MEN1KMT2AGFERMAPK1POLB
SCHEMBL27100754 0.93 MEN1 (0.41) MEN1KMT2AGFERMAPK1POLB
SCHEMBL27100757 0.90 MEN1 (0.37) MEN1KMT2AGFERALDH1A1MAPT
SCHEMBL27100800 0.90 ALDH1A1 (0.47) MEN1KMT2AGFERTDP2ALDH1A1
SCHEMBL27100747 0.86 ALDH1A1 (0.34) MAPK1POLBALDH1A1MAPTTDP1
SCHEMBL27100792 0.86 ALDH1A1 (0.35) MEN1KMT2AGFERALDH1A1MAPT
SCHEMBL27100753 0.86 ALDH1A1 (0.33) MEN1KMT2AGFERMAPK1POLB
SCHEMBL27100813 0.84 ALDH1A1 (0.36) MEN1KMT2AGFERMAPK1POLB
SCHEMBL27100763 0.84 MEN1 (0.37) MEN1KMT2AGFERALDH1A1MAPT
SCHEMBL27100790 0.84 SMN1; SMN2 (0.42) MEN1KMT2AMAPK1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed