SCHEMBL2710484

SCHEMBL2710484

Fc1cc2c(-c3cc(F)c(F)c(F)c3)c3ccccc3c(-c3cc(F)c(F)c(F)c3)c2cc1F

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.36
ACHE P22303 4/20 0.32
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP1B1 Q16678 1/20 0.30
TP53 P04637 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710319 0.94 ACHE (0.38) HPRT1ACHECYP1A2LMNA
SCHEMBL2709632 0.93 HPRT1 (0.35) HPRT1ACHECYP1A2NPC1ALDH1A1
SCHEMBL2710039 0.92 HPRT1 (0.32) HPRT1
SCHEMBL12086167 0.92 NPC1 (0.33) HPRT1NPC1ALDH1A1LMNAOPRD1
SCHEMBL2712231 0.92 CYP1A1 (0.36) HPRT1ACHECYP1A1CYP1A2CYP1B1
SCHEMBL2725033 0.88 CYP1A1 (0.38) ACHECYP1A1CYP1A2CYP1B1TP53
SCHEMBL2711234 0.87 ACHE (0.41) ACHECYP1A2LMNA
SCHEMBL2710377 0.86 HPGD (0.39) HPRT1ACHECYP1A2ALDH1A1LMNA
SCHEMBL12086057 0.85 NPC1 (0.36) HPRT1ACHENPC1ALDH1A1LMNA
SCHEMBL2713398 0.85 KDM4E (0.32) HPRT1ACHECYP1A2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 HPRT1 1454/4885ACHE 187/4885CYP1A1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.