Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837328 | 1.00 | NAMPT (0.51) | NAMPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL29181014 | 0.88 | NAMPT (0.52) | NAMPTKMT2AKDM4EMAPTTHRB | |
| SCHEMBL12121564 | 0.88 | ACMSD (0.57) | NAMPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL23858326 | 0.85 | NAMPT (0.53) | NAMPTKMT2AKDM4EMAPTTHRB | |
| SCHEMBL30075838 | 0.85 | NAMPT (0.53) | NAMPTKMT2AKDM4EMAPTTHRB | |
| SCHEMBL15380874 | 0.84 | SMN1; SMN2 (0.56) | NAMPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL31130020 | 0.84 | NAMPT (0.52) | NAMPTKMT2AKDM4EMAPTTHRB | |
| SCHEMBL7398901 | 0.83 | PDE4B (0.61) | NAMPTKMT2AMEN1KDM4EHPGD | |
| SCHEMBL19092740 | 0.82 | NAMPT (0.53) | NAMPTKMT2AKDM4EMAPTTHRB | |
| SCHEMBL29776648 | 0.82 | NAMPT (0.53) | NAMPTKMT2AKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756703-A | Naphthalimide-based coronavirus papain-like protease inhibitors | 广州国家实验室 | 2024-03-26 | — | — | CN | disclosed |